Rutgers Patents

N-substituted monomers and polymers

2011-08-30T08:15:00.001-07:00

Patent Number: 8008528

Inventor(s): Kohn; Joachim B. (Piscataway, NJ), Bolikal; Durgadas (Edison, NJ), Schut; Jaap (Rotterdam, NL), Baluca; Ernest G. (San Diego, CA)

Date Issued: 8/30/2011

Abstract: Biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an amide group, wherein said amide groups are N-substituted and the N-substituent and degree of N-substitution are effective to lower the melt viscosity, the solution viscosity, or both, compared to the same polymer without N-substitution.

USPTO # 8008528

Use of recycled plastics for structural building forms

2011-08-30T08:15:00.000-07:00

Patent Number: 8008402

Inventor(s): Lynch; Jennifer K. (Franklin Park, NJ), Nosker; Thomas J. (Stockton, NJ), Lehman; Richard (Princeton, NJ), Idol; James D. (Columbus, OH), Van Ness; Kenneth (Lexington, VA), Renfree; Richard W. (Scotch Plains, NJ), Renfree, legal representative; Maryann (Scotch Plains, NJ)

Date Issued: 8/30/2011

Abstract: Modular plastic structural composites formed from a mixture of (A) high density polyolefin and one or both of: (B) a thermoplastic-coated fiber material, or (C) polystyrene, poly(methyl methacrylate), or a combination thereof. Composites molded in the form of I-Beams and bridges constructed therefrom are also disclosed.

USPTO # 8008402

Resample and composite engine for real-time volume rendering

2011-08-23T08:15:00.000-07:00

Patent Number: RE42,638

Inventor(s): Ray; Harvey (Longmont, CO), Silver; Deborah (East Brunswick, NJ)

Date Issued: 8/23/2011

Abstract: The present invention is a digital electronic system for rendering a volume image in real time. The system accelerators the processing of voxels through early ray termination and space leaping techniques in the projection guided ray casting of the voxels. Predictable and regular voxel access from high-speed internal memory further accelerates the volume rendering. Through the acceleration techniques and devices of the present invention real-time rendering of parallel and perspective views, including those for stereoscopic viewing, are achieved.

USPTO #RE 42,638

Use of recycled plastics for structural building forms

2011-08-16T08:15:00.001-07:00

Patent Number: 7996945

Inventor(s): Nosker; Thomas (Stockton, NJ), Renfree; Richard (Scotch Plains, NJ), Renfree, legal representative; Maryann (Scotch Plains, NJ), Kerstein; James (Watchung, NJ), Simon; Louis (Branchburg, NJ)

Date Issued: 8/16/2011

Abstract: Modular plastic structural composites having a web section disposed along a horizontal axis and at least one flange section disposed along a horizontal axis parallel thereto and integrally molded to engage the top or bottom surface of the web section, wherein said composite is formed from a mixture of (A) high density polyolefin and (B) a thermoplastic-coated fiber material, poly-styrene, or a combination thereof. Composites molded in the form of I-Beams and bridges constructed therefrom are also disclosed.

USPTO #7996945

Hydroxyapatite with controllable size and morphology

2011-08-16T08:15:00.000-07:00

Patent Number: 7998219

Inventor(s): Riman; Richard E. (Belle Mead, NJ), Burukhin; Alexander (Moscow, RU), Zlotnikov; Eugene (Highland Park, NJ), Haders; Dan (Somerset, NJ)

Date Issued: 8/16/2011

Abstract: A ceramic powder of non-agglomerated non-aggregated phase-pure hydroxyapatite having a controllable morphology. Also presented is a film of phasepure crystalline hydroxyapatite grains having a controllable morphology. Methods for preparing the same are also provided.

USPTO # 7998219

Multifunctional biosensor based on ZnO nanostructures

2011-08-02T08:15:00.000-07:00

Patent Number: 7989851

Inventor(s): Lu; Yicheng (East Brunswick, NJ), Chen; Ying (Piscataway, NJ), Zhang; Zheng (Belle Mead, NJ)

Date Issued: 8/2/2011

Abstract: The present invention provides the multifunctional biological and biochemical sensor technology based on the integration of ZnO nanotips with bulk acoustic wave (BAW) devices, particularly, quartz crystal microbalance (QCM) and thin film bulk acoustic wave resonator (TFBAR). ZnO nanotips provide giant effective surface area and strong bonding sites. Furthermore, the controllable wettability of ZnO nanostructured surface dramatically reduces the liquid consumption and enhances the sensitivity of the biosensor device.

USPTO #7989851

Medical devices employing novel polymers

2011-07-26T08:15:00.000-07:00

Patent Number: 7985415

Inventor(s): Giroux; Karen J. (Piscataway, NJ)

Date Issued: 7/26/2011

Abstract: Medical devices with at least one surface comprising a polymer or polymers on the surface are provided. The polymer or polymers are capable of breaking down (e.g., including, but not limited to, hydrolyzing) in the physiologic milieu to form an active agent or agents under physiologic conditions, and can contain other active agents dispersed within or appended to the polymer matrix. Methods of delivering an active agent to an interior surface of a vein or artery are also provided.

USPTO # 7985415

Moldable and low-temperature cure high-temperature composites

2011-07-12T08:15:00.000-07:00

Patent Number: 7976962

Inventor(s): Balaguru; Perumalsamy Naidu (Milltown, NJ)

Date Issued: 7/12/2011

Abstract: A method for preparing a high-temperature heat-resistant composite material by combining a mixture of submicron alumina powder and submicron silica powder, wherein the ratio of alumina to silica is from about 4:1 to about 5:1, submicron Group II metal oxide powder, and a Group I metal silicate solution to form a slurry, wherein the weight of the Group II metal oxide powder is an amount corresponding to about 5% to about 10% of the weight of the silicate solution; contacting reinforcing high-temperature resistant fibers with the slurry to form a composite precursor composition; and curing the composition at a temperature sufficient to produce the high-temperature heat-resistant composite material capable of resisting temperatures up to about 1400.degree. C. Composite materials prepared according to the method and articles incorporating the material are also presented.

A method for preparing a high-temperature heat-resistant composite material by combining a mixture of submicron alumina powder and submicron silica powder, wherein the ratio of alumina to silica is from about 4:1 to about 5:1, submicron Group II metal oxide powder, and a Group I metal silicate solution to form a slurry, wherein the weight of the Group II metal oxide powder is an amount corresponding to about 5% to about 10% of the weight of the silicate solution; contacting reinforcing high-temperature resistant fibers with the slurry to form a composite precursor composition; and curing the composition at a temperature sufficient to produce the high-temperature heat-resistant composite material capable of resisting temperatures up to about 1400.degree. C. Composite materials prepared according to the method and articles incorporating the material are also presented.

USPTO #7976962

Compositions and methods for the protection of substrates from heat flux and fire

2011-06-07T08:15:00.000-07:00

Patent Number: 7955996

Inventor(s): Nosker; Thomas (Stockton, NJ), Lynch; Jennifer K (Franklin Park, NJ), Mazar; Mark N (Piscataway, NJ), Nosker; Patrick L (Stockton, NJ)

Date Issued: 6/7/2011

Abstract: A flame or heat flux protective coating composition, which includes a dispersion of fiberglass, hollow glass spheres, or a combination of both in silicone. A flame or heat flux protective sheet, which includes hollow glass spheres dispersed in silicone in a sheet form or fiberglass and silicone in a sheet form, wherein the fiberglass is dispersed in the silicone or the fiberglass is a woven cloth coated with the silicone is also presented. Articles incorporating the flame or heat flux protective coating or sheet form and methods for coating an article with the flame or heat flux protective coating composition are also presented.

USPTO # 7955996

Bismuth fluoride based nanocomposites as electrode materials

2011-05-24T06:18:00.000-07:00

Patent Number: 7947392

Inventor(s): Amatucci; Glenn G. (Peapack, NJ), Badway; Fadwa (Old Bridge, NJ), Bervas; Mathieu (Chatou, FR)

Date Issued: 5/24/2011

Abstract: The present invention relates to primary and secondary electrochemical energy storage systems, particularly to such systems as battery cells, which use materials that take up and release ions as a means of storing and supplying electrical energy. The present positive electrode composition comprises a nanocrystalline bismuth fluoride compound, which comprises Bi.sup.+3, and has a maximum energy density of 7170 Wh/l.sup.-1.

USPTO 7947392

Method and apparatus for using bayesian networks for localization

2011-05-03T06:18:00.000-07:00

Patent Number: 7937339

Inventor(s): Martin; Richard (Metuchen, NJ), Kleisouris; Konstantinos (New Brunswick, NJ)

Date Issued: 5/3/2011

Abstract: The invention is a technique for performing sampling in connection with Markov Chain Monte Carlo simulations in which no attempt is made to limit the selected samples to a selected slice of the entire sample domain, as is typical in Markov Chain Monte Carlo sampling. Rather, samples are taken from the entire domain and any samples that fall below a randomly selected probability density level are discarded.

USPTO 7937339

Method and system for execution monitor-based trusted computing

2011-04-19T06:18:00.000-07:00

Patent Number: 7930733

Inventor(s): Iftode; Liviu (Princeton, NJ), Xu; Gang (Piscataway, NJ)

Date Issued: 4/19/2011

Abstract: A system and method of providing trusted service transactions includes associating a commitment with a remote service. The commitment includes a trusted list of runtime dependencies to execute a transaction. The method includes monitoring an actual list of runtime dependencies invoked during execution of the transaction using a trusted monitor. Execution is blocked if a deviation of the actual list from the trusted list is detected. Therefore, a completed transaction is allowed only if no deviation is found between the trusted and invoked list of runtime dependencies. A certificate authority in cooperation with software vendors preferably provide a signed commitment. The commitment is delivered by the provider to a user upon request and verified by the requester. The transaction is then executed by the user. Therefore, trust is verified before and during the transaction and privacy of data is guaranteed after completion.

USPTO 7930733

Uniform shear application system and methods relating thereto

2011-04-05T06:18:00.000-07:00

Patent Number: 7918410

Inventor(s): Muzzio; Fernando J. (Sparta, NJ)

Date Issued: 4/5/2011

Abstract: Disclosed herein is a shear application system for applying substantially uniform amounts of shear throughout a powder sample. The shear application system preferably includes a cylinder assembly having an inner cylinder, a housing, an inner set of lugs, and an outer set of lugs. The inner cylinder has an external cylindrical surface and the housing has an internal cylindrical surface concentric with said external cylindrical surface. The internal and external cylindrical surfaces form an annular chamber therebetween. Each one of the lugs of the inner set extend radially outward from the external cylindrical surface, and each one of the lugs of the outer set extend radially inward from the internal cylindrical surface and are substantially uniformly spaced. The shear application system preferably includes drive means mechanically connected to the inner cylinder and control means electrically connected to the drive means.

USPTO 7918410

Lily plant named `BJM 005`

2011-03-08T06:18:00.001-08:00

Patent Number: PP21,767

Inventor(s): Merritt; Richard H. (Bridgewater, NJ)

Date Issued: 3/8/2011

Abstract: A new and distinct lily plant substantially as shown and described, characterized by (1) stem thickness supported by flower crown without bending (10-11 mm in diameter); (2) straight stems with even leaf distribution from bottom to top (95-115 leaves per plant); (3) flower crown compact; (4) flower sizes (11 cm long 6 cm wide at open stage); (5) continuous blooms for two to four weeks; (6) coloration of leaves uniform from bottom to top; (7) height of plant around 40 cm; and (8) red to purple flowers.

USPTO PP21767

Dual catalyst system for alkane metathesis

2011-03-08T06:18:00.000-08:00

Patent Number: 7902417

Inventor(s): Goldman; Alan S. (Highland Park, NJ), Brookhart; Maurice (Carrboro, NC), Roy; Amy H. (Laurel, MD), Ahuja; Ritu (Highland Park, NJ), Huang; Zheng (Chapel Hill, NC)

Date Issued: 3/8/2011

Abstract: A method of converting at least one first alkane to a mixture of at least one low molecular weight alkane (optionally also including additional lower and/or higher molecular weight alkanes) and at least one high molecular weight alkane, comprising: reacting a first alkane in the presence of dual catalyst system comprising a first catalyst (i.e., a hydrogen transfer catalyst and preferably an iridium pincer complex catalyst) and a second catalyst (i.e., a metathesis catalyst) to produce a mixture of low and high molecular weight alkanes.

USPTO 7902417

Lily plant named 'BJM 004'

2011-03-01T06:18:00.000-08:00

Patent Number: PP21,752

Inventor(s): Merritt; Richard H. (Bridgewater, NJ)

Date Issued: 3/1/2011

Abstract: A new and distinct lily plant substantially as shown and described, characterized by (1) stem thickness supported by flower crown without bending (9 mm in diameter); (2) straight stems with even leaf distribution from bottom to top (102 leaves per plant); (3) flower crown compact (around 12.times.12 cm); (4) flower sizes large (11-14 cm long 11-14 cm wide at open stage); (5) continuous blooms for two to four weeks; (6) coloration of leaves uniform from bottom to top; (7) height of plant around 30 cm; and (8) red flowers.

USPTO PP21752

Apparatuses and methods for determining protease activity

2011-02-08T06:18:00.000-08:00

Patent Number: 7883863

Inventor(s): Ward; William W. (Metuchen, NJ), Swiatek; Gavin C. (Highland Park, NJ)

Date Issued: 2/8/2011

Abstract: The present invention relates to compositions and an apparatuses for determining protease activity. The compositions of the invention contain a reporter protein fused to at least one protease cleavage sequence, and a linker for attaching the protease cleavage sequence to a solid support. Methods for determining protease activity and characterizing proteases are also provided.

USPTO 7883863

Methods for reducing circulating glucose levels

2011-01-25T06:18:00.000-08:00

Patent Number: 7875300

Inventor(s): Raskin; Ilya (Manalapan, NJ), Ilic; Nebojsa (Highland Park, NJ), Kuhn; Peter (Colonia, NJ)

Date Issued: 1/25/2011

Abstract: The invention relates to methods of reducing circulating glucose levels with compositions obtained from botanical sources. More specifically, the invention relates to methods of treating individuals whom wish to reduce their circulating glucose levels, particularly individuals having elevated circulating glucose levels, with an extract product of Aframomum melegueta.

USPTO 7875300

Method for anaerobic degradation of fuel oxygenates and similar compounds

2011-01-11T06:18:00.000-08:00

Patent Number: 7867750

Inventor(s): Haggblom; Max M. (New York, NY), Somsamak; Piyapawn (Nan, TH)

Date Issued: 1/11/2011

Abstract: The present invention relates to a method for remediating fuel oxygenate-contaminated soil, sediment or groundwater comprising combining at least one natural microorganism source with at least one methoxylated phenolic compound under anaerobic conditions. The invention also relates to a method for increasing the rate of remediation of fuel oxygenate-contaminated soil.

USPTO 7867750

Topoisomerase-targeting agents

2010-12-28T06:18:00.000-08:00

Patent Number: 7858627

Inventor(s): LaVoie; Edmond J. (New Brunswick, NJ), Ruchelman; Alexander L. (New Brunswick, NJ), Liu; Leroy F. (New Brunswick, NJ)

Date Issued: 12/28/2010

Abstract: The invention provides compounds of formula I or formula II: ##STR00001## wherein: the bond represented by is a single bond or a double bond, and R.sub.1--R.sub.5, X, and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I or II, processes for preparing compounds of formula I or II, intermediates useful for preparing compounds of formula I or II, and therapeutic methods for treating cancer and other topoisomerase related conditions using compounds of formula I or II.

USPTO 7858627

Moldable and low-temperature cure high-temperature composites

2010-12-21T06:18:00.000-08:00

Patent Number: 7854882

Inventor(s): Balaguru; Perumalsamy Naidu (Milltown, NJ)

Date Issued: 12/21/2010

USPTO 7854882

Flame-retardant coating

2010-12-14T06:18:00.000-08:00

Patent Number: 7851536

Inventor(s): Nosker; Thomas (Stockton, NJ), Mazar; Mark (Piscataway, NJ), Lynch; Jennifer (Franklin Park, NJ), Nosker; Patrick (Stockton, NJ)

Date Issued: 12/14/2010

Abstract: A flame-retardant coating composition, which includes a cross-linked thermosetting polymer and a metal hydroxide. A precursor composition for use in preparing the flame retardant-coating is also presented, wherein the precursor composition includes a cross-linked thermosetting polymer varnish, a metal hydroxide, an alcohol, and water. A method for coating an article with a flame-retardant coating layer and articles incorporating the flame-retardant coating are also presented.

USPTO 7851536

Drug-polymer conjugates coupled to a peptidic carrier

2010-12-07T06:18:00.000-08:00

Patent Number: 7846893

Inventor(s): Sinko; Patrick J. (Lebanon, NJ), Stein; Stanley (East Brunswick, NJ), Gunaseelan; Simi (Highland Park, NJ), Pooyan; Shahriar (Mount Kisco, NY), Wan; Li (Randolph, NJ), Zhang; Xiaoping (Edison, NJ)

Date Issued: 12/7/2010

Abstract: Monodisperse macromolecular conjugate compositions of a peptidic carrier irreversibly or reversibly conjugated with one or more effectors and one or more therapeutic agents, wherein at least one effector or therapeutic agent is attached to a pendant reactive group on said peptidic carrier via a water-soluble polymer. Monodispersity is obtained through the use of orthogonal and separate conjugation reactions.

USPTO 7846893

Hydrazide compounds with angiogenic activity

2010-11-23T06:18:00.000-08:00

Patent Number: 7838122

Inventor(s): Kohn; Joachim B. (Piscataway, NJ), Labazzo; Kristen S. (North Brunswick, NJ), Bolikal; Durgadas (Edison, NJ)

Date Issued: 11/23/2010

Abstract: Compounds exhibiting angiogenic properties incorporating the structure of Formula I: R.sub.3--NH--NH--C(.dbd.O)--R.sub.2--P--R.sub.1 (I) wherein P is a water-soluble, biodegradable polymer, R.sub.1 is hydrogen, lower alkyl, lower alkoxy or --R.sub.2--C(.dbd.O)--NH--NH--R.sub.3; each R.sub.2 is independently --CH.sub.2--, --NH-- or O; and each R.sub.3 is independently hydrogen or a residue of a naturally occurring alpha-L-amino acid or dipeptide thereof. Polymer networks crosslinked with hydrazide compounds are also disclosed, together with implantable medical devices incorporating the compounds and crosslinked polymers, and angiogenesis-promoting treatment methods, including wound-treatment methods.

USPTO 7838122

Use of recycled plastics for structural building forms

2010-09-14T06:18:00.000-07:00

Patent Number: 7795329

Date Issued: 9/14/2010

Abstract: Modular plastic structural composites having a web section disposed along a horizontal axis and at least one flange section disposed along a horizontal axis parallel thereto and integrally molded to engage the top or bottom surface of the web section, wherein said composite is formed from a mixture of (A) high density polyolefin and (B) a thermoplastic-coated fiber material, polystyrene, or a combination thereof. Composites molded in the form of I-Beams and bridges constructed therefrom are also disclosed.

USPTO 7795329

Sol-gel fabrication of thin-film electrolyte in an oxygen generator

2010-09-07T06:18:00.000-07:00

Patent Number: 7790221

Inventor(s): Chandran; Ravi R. (Edison, NJ), Klein; Lisa (Highland Park, NJ), Mege; Sandra (Paris, FR)

Date Issued: 9/7/2010

Abstract: An electrochemical cell that receives an inlet stream of air and produces an outlet stream of a high oxygen concentration of gas. The cell is made up of a plurality of layers and preferably a porous electrolyte comprised of yttria stabilized zirconia (YSZ) that allows only oxygen ions to pass therethrough and which is covered on its sides with electrodes comprised of lanthanum strontium manganate (LSM) which in turn are coated with a layer of platinum to aid in the even distribution of the electrical current. An electrical current is passed through the electrodes to produce a voltage difference therebetween. The layers of YSZ and LSM are formed by a sol-gel process.

USPTO 7790221

Solubilized topoisomerase poisons

2010-08-24T06:18:00.001-07:00

Patent Number: 7781587

Inventor(s): LaVoie; Edmond J. (Princeton Junction, NJ), Ruchelman; Alexander L. (Robbinsville, NJ), Liu; Leroy F. (Bridgewater, NJ)

Date Issued: 8/24/2010

Abstract: The invention provides compounds of formula I: ##STR00001## wherein A, B, W, Y, Z, and R.sub.1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.

USPTO 7781587

Method and apparatus for globally approximating quantiles in a distributed monitoring environment

2010-08-24T06:18:00.000-07:00

Patent Number: 7783647

Inventor(s): Cormode; Graham R. (Summit, NJ), Garofalakis; Minos N. (San Francisco, CA), Muthukrishnan; Shanmugavelayutham (Washington, DC), Rastogi; Rajeev (Bangalore, IN)

Date Issued: 8/24/2010

Abstract: The invention comprises a method and apparatus for determining a rank of a query value. Specifically, the method comprises receiving a rank query request, determining, for each of the at least one remote monitor, a predicted lower-bound rank value and upper-bound rank value, wherein the predicted lower-bound rank value and upper-bound rank value are determined according to at least one respective prediction model used by each of the at least one remote monitor to compute the at least one local quantile summary, computing a predicted average rank value for each of the at least one remote monitor using the at least one predicted lower-bound rank value and the at least one predicted upper-bound rank value associated with the respective at least one remote monitor, and computing the rank of the query value using the at least one predicted average rank value associated with the respective at least one remote monitor.

7783647

Lily plant named `BJM 006`

2010-08-17T06:18:00.000-07:00

Patent Number: PP21,206

Inventor(s): Merritt; Richard H. (Bridgewater, NJ)

Date Issued: 8/17/2010

Abstract: A new and distinct lily plant substantially as shown and described, characterized by 1) stem thickness supported by flower crown (8 to 10 mm in diameter); (2) straight stems with even leaf distribution from bottom to top (more than 50 leaves per plant); (3) flower crown compact (around 36 cm); and flat with pericel lengths variable in length (1 to 8 cm); (4) flower sizes large (9-16 cm long 20-25 cm wide at open stage); (5) continuous blooms for two to four weeks; (6) coloration of leaves uniform from bottom to top; (7) height of plant around 40 cm; and (8) orange flowers.

PP21206

Optically transparent nanocomposite materials

2010-08-10T06:18:00.000-07:00

Patent Number: 7771619

Inventor(s): Riman; Richard E. (Belle Mead, NJ), Ballato; John (Clemson, SC)

Date Issued: 8/10/2010

Abstract: Optically transparent composite materials in which solid solution inorganic nanoparticles are dispersed in a host matrix inert thereto, wherein the nanoparticles are doped with one or more active ions at a level up to about 60 mole % and consist of particles having a dispersed particle size between about 1 and about 100 nm, and the composite material with the nanoparticles dispersed therein is optically transparent to wavelengths at which excitation, fluorescence or luminescence of the active ions occur. Luminescent devices incorporating the composite materials are also disclosed.

7771619

Technology for continuous folding of sheet materials into a honeycomb-like configuration

2010-07-20T06:18:00.001-07:00

Patent Number: 7758487

Inventor(s): Elsayed; Elasyed A. (East Brunswick, NJ), Basily; Basily B. (Piscataway, NJ)

Date Issued: 7/20/2010

Abstract: A machine and method for the continuous folding of sheet material into different three-dimensional patterns. The innovative machine and method folds sheet material by force converging the sheet to a final stage that imparts a final fold or pattern into the sheet material, the patterns selectively including one of a Chevron pattern, a honeycomb-like pattern, a double-sided inclined folded core structure, and singular inclined direction folded core structure sheet material.

7758487

Male asparagus hybrid plant `NJ953`

2010-07-20T06:18:00.000-07:00

Patent Number: PP21,170

Inventor(s): Chin; Chee-kok (Holmdel, NJ), Garrison; Stephen A. (Pittsgrove, NJ), Kinelski; John J. (Princeton, NJ)

Date Issued: 7/20/2010

Abstract: A hybrid male asparagus plant (Asparagus officinalis) denoted `NJ953` has many desirable traits including vigorous plant growth, high yield, attractive spear morphology, good resistance to rust (Puccinia asparagi) and good field tolerance to asparagus root rot (Fusarium oxysporum) and asparagus crown rot (Fusarium mondiforme). These desirable traits have been shown to be transmissible to its progenies. The invention relates to plants and plant parts of `NJ953` plant. The invention further relates to hybrid asparagus seeds and plants produced by crossing the asparagus `NJ953` plant with another asparagus plant.

PP21170

Virtual tags and the process of virtual tagging

2010-06-01T06:18:00.000-07:00

Patent Number: 7730395

Inventor(s): Imielinski; Tomasz (Princeton, NJ), Sgro; Vince (Somerset, NJ), Smith; Don (East Brunswick, NJ)

Date Issued: 6/1/2010

Abstract: The present invention relates to a method and system for transformation of an electronic document through learning transformation rules during training from the original electronic document using visual user feedback and applying the learned transformation rules to either the original electronic document or a second electronic document having a similar structure as the original document or all future instances of the original electronic document. Accordingly, the transformed document is customized to the user's preference learned during training. Preferably, the transformed document is created in a queriable form. For example, the original electronic document can be defined any type of mark-up language or electronic document generation language, such as Hypertext mark-up language (HTML), extended mark-up language (XML), portable data file (PDF) or Microsoft.RTM. Word, and the like and the transformed document is defined in a queriable language such as (XML) views and the like. For example, a virtual page can be a customization of an instance of a Web page which can be used to transform all future instances of the original Web page. Alternatively, the virtual page is formed form a customization of an original electronic document, such as a chapter in a book, which is applied to a second electronic document having a similar structure, such as all chapters in the book.

7730395

Polyarylates for drug delivery and tissue engineering

2010-05-25T06:18:00.000-07:00

Patent Number: 7722896

Inventor(s): Kohn; Joachim B. (Plainfield, NJ), Pulapura; Satish (Bridgewater, NJ), Schwartz; Arthur (East Windsor, NJ), Bahulekar; Raman (Edison, NJ)

Date Issued: 5/25/2010

Abstract: Biocompatible polyarylates of diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed.

7722896

Polycrystalline material having a plurality of single crystal particles

2010-04-27T06:18:00.000-07:00

Patent Number: 7704321

Inventor(s): Riman; Richard (Belle Mead, NJ), McCandlish; Larry (Highland Park, NJ), Liu; Xiangyuan (Highland Park, NJ)

Date Issued: 4/27/2010

Abstract: Polycrystalline materials of macroscopic size exhibiting Single-Crystal-Like properties are formed from a plurality of Single-Crystal Particles, having Self-Aligning morphologies and optionally bonded together and aligned along at least one, and up to three, crystallographic directions.

7704321

Method and apparatus for making and detecting a document verification indicator using optical pattern encryption

2010-04-20T06:18:00.000-07:00

Patent Number: 7699236

Inventor(s): Dana; Kristin (Staten Island, NY), Livescu; Gabriela (Marlboro, NJ), Lu; Yicheng (East Brunswick, NJ)

Date Issued: 4/20/2010

Abstract: A method and apparatus for creating and detecting an optically encoded document having a uniquely designed document verification indicator is disclosed. One embodiment includes applying a spatially varying Brewster angle pattern on a substrate. Another embodiment includes an apparatus for detecting the spatially varying Brewster angle pattern including a light source, a slit aperture, a polarizer, at least one parabolic mirror, and an image capturing device.

7699236

Methods and compositions for treating melanoma

2010-04-06T06:18:00.001-07:00

Patent Number: 7691377

Inventor(s): Goydos; James S. (East Brunswick, NJ), Chen; Suzie (Highland Park, NJ)

Date Issued: 4/6/2010

Abstract: A method for inhibiting melanoma cell growth in a patient by administering to the patient a therapeutically effective amount of a glutamate release inhibitor, a GRM1 antagonist, or a combination thereof

7691377

Technology for continuous folding of sheet materials

2010-04-06T06:18:00.000-07:00

Patent Number: 7691045

Inventor(s): Basily; Basily B. (Piscataway, NJ), Elsayed; Elsayed A. (East Brunswick, NJ), Kling; Daniel (Ringoes, NJ)

Date Issued: 4/6/2010

Abstract: A machine and method for the continuous folding of sheet material into difference three-dimensional patterns is featured. The innovative machine and method folds sheet material by force converging the sheet to a final stage that imparts a final fold or pattern. Unique programming allows for the change of convergence sequencing and change of materials.

7691045

Field-effect transistors with weakly coupled layered inorganic semiconductors

2010-03-02T06:18:00.001-08:00

Patent Number: 7670887

Inventor(s): Bucher; Ernst (Summit, NJ), Gershenson; Michael E. (Highland Park, NJ), Kloc; Christian (New Providence, NJ), Podzorov; Vitaly (Piscataway, NJ)

Date Issued: 3/2/2010

Abstract: A field-effect transistor includes source, drain, and gate electrodes; a crystalline or polycrystalline layer of inorganic semiconductor; and a dielectric layer. The layer of inorganic semiconductor has an active channel portion physically extending from the source electrode to the drain electrode. The inorganic semiconductor has a stack of 2-dimensional layers in which intra-layer bonding forces are covalent and/or ionic. Adjacent ones of the layers are bonded together by forces substantially weaker than covalent and ionic bonding forces. The dielectric layer is interposed between the gate electrode and the layer of inorganic semiconductor material. The gate electrode is configured to control a conductivity of an active channel part of the layer of inorganic semiconductor.

7670887

Interspecific Ilex hybrid plant designated ‘Spartan’

2010-03-02T06:18:00.000-08:00

Patent Number: PP20,804

Inventor(s): Orton; Elwin R. (Hillsborough, NJ), Gant; David A. (Wall Township, NJ)

Date Issued: 3/2/2010

Abstract: A new and distinct variety of evergreen shrub holly distinguished in that it combines from three species (Ilex rugosa, I. integra, and I. pernyi), as well as exhibiting desirable landscape and production traits which distinguish it from other forms of Ilex. Plants of the new variety exhibit a moderately vigorous rate of growth, develop a dense, self-compacting, moderately broad conical form of moderate size, possess small, shiny, dark green leaves with a beautiful finely rugose surface and non-spiny margins (consumer friendly) with bright red fruit displayed on wood of the previous season's growth, and are outstanding for their high level of winter hardiness.

PP20804

Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby

2010-02-23T06:18:00.001-08:00

Patent Number: 7666398

Inventor(s): Uhrich; Kathryn E. (Hoboken, NJ)

Date Issued: 2/23/2010

Abstract: Polyanhydrides which link low molecular weight drugs containing a carboxylic acid group and an amine, thiol, alcohol or phenol group within their structure into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug delivery systems via these polyanhydride linkers as well as methods of administering low molecular weight drugs to a host via the polymeric drug delivery systems.

7666398

A site specific recombination system and methods of use thereof are disclosed for manipulating the genome of higher plants.

2010-02-23T06:18:00.000-08:00

Patent Number: 7667093

Inventor(s): Maliga; Pal (East Brunswick, NJ), Corneille; Sylvie (Highland Park, NJ), Lutz; Kerry (Lawrenceville, NJ)

Date Issued: 2/23/2010

Abstract: A site specific recombination system and methods of use thereof are disclosed for manipulating the genome of higher plants.

7667093

Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent

2010-02-16T06:18:00.000-08:00

Patent Number: 7662864

Inventor(s): Kanamathareddy; Suseela (Highland Park, NJ), Goodrich; Stephen (St. John, IN), Choe; Yun (Green Brook, NJ)

Date Issued: 2/16/2010

Abstract: Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.

7662864

Isolated species of Steinernematid nematode and methods of white grub control therewith

2010-01-05T06:18:00.000-08:00

Patent Number: 7641913

Inventor(s): Koppenhofer; Albrecht M. (Lawrenceville, NJ)

Date Issued: 1/5/2010

Abstract: An isolated Steinernematid nematode of the species Steinernema scarabaei (ATCC accession No. PTA-6988) is provided which is entomopathogenic to the larvae of scarab beetles, e.g., Japanese beetle (Popillia japonica), oriental beetles (Exomala (=Anomala) orientalis), European chafer (Rhizotrogus majalis), Asiatic garden beetle (Maladera castanea), masked chafers (Cyclocephala spp.), and May/June beetles (Phyllophagaspp). A biopesticide composition is provided which comprises an insecticidally effective amount of Steinernema scarabaei. Biopesticide compositions are described which, in addition to Steinernema scarabaei, further comprise at least one neonicotinoid insecticide, e.g., imidacloprid. Methods are provided for controlling the larvae of at least one species of scarab beetle comprising applying a biopesticide composition to the locus of the larvae wherein the composition comprises an insecticidally effective amount of an isolated entomopathogenic nematode of the species Steinernema scarabaei.

7641913

Compositions and methods for diagnosing autism

2009-12-08T06:18:00.000-08:00

Patent Number: 7629123

Inventor(s): Millonig; James H. (Princeton Junction, NJ), Brzustowicz; Linda (Madison, NJ), Gharani; Neda (North Brunswick, NJ)

Date Issued: 12/8/2009

Abstract: Mutations located within the gene encoding the homeobox transcription factor, ENGRAILED 2 (EN2), have now been identified as molecular markers associated with susceptibility for autism and related disorders. Thus, the present invention relates to compositions in the form of diagnostic kits, primers and target sequences, for use in methods for determining the predisposition, the onset or the presence of autism spectrum disorder in a mammal. Moreover, therapeutic methods for treating a person inflicted with, or predisposed to, an autism spectrum disorder based upon modulating the level or activity of EN2 are also provided.

7629123

Transition metal fluoride: carbon nanoamalgam rechargeable battery cell electrode material

2009-12-01T06:18:00.000-08:00

Patent Number: 7625671

Inventor(s): Amatucci; Glenn G. (Peapack, NJ)

Date Issued: 12/1/2009

Abstract: A safe and economical electrochemically active material useful in rechargeable battery cell electrode compositions comprises a nanostructure amalgam of a transition metal fluoride and carbon. The nanoamalgam may be prepared by subjecting a precursor mixture of a transition metal fluoride, such as FeF.sub.3, and carbon to extreme, high energy impact comminution milling which results in the conversion of the mixture to a unique and distinct nanostructure material. When incorporated as active electrode material in lithium battery cell fabrications, the nanoamalgam enables the attainment of stable specific discharge capacities in the range of 250 to 500 mAh/g.

7625671

Analytical methods and apparatus

2009-11-10T06:18:00.000-08:00

Patent Number: 7616305

Inventor(s): Murnick; Daniel E. (Bernardsville, NJ)

Date Issued: 11/10/2009

Abstract: A gaseous analyte including a small amount of a multiatomic moiety incorporating a particular isotope, such as .sup.14CO.sub.2 is subjected to a standing optical wave at a resonant wavelength of the moiety while maintaining the moiety in an excited condition, such as in a gas discharge. The standing optical wave may be applied by a laser having a sample cell containing the analyte within the laser cavity. Monitoring an induced effect such as the optogalvanic effect yields a signal directly related to the quantity of the moiety. The test can detect quantities of the moiety of an attomole or less, and in some cases on the order of 100 molecules.

7616305

Quartz Crystal Resonator

2009-10-27T06:18:00.000-07:00

Patent Number: 7608986

Inventor(s): Yong; Yook-Kong (Princeton, NJ), Patel; Mihir S (Highland Park, NJ), Tanaka; Masako (Okaya, JP)

Date Issued: 10/27/2009

Abstract: A quartz crystal resonator includes a quartz crystal resonator element having a main surface including an X axis (electrical axis) and a Z' axis of an inclination rotated at an angle (y) equal to or greater than 36.4 degrees and equal to or smaller than, 40.5 degrees from a Z axis (optical axis) around the X axis, a main vibrating portion vibrating at a predetermined resonance frequency (f) and a supporting portion integrally formed with the main vibrating portion in such a manner as to be formed peripherally to surround the main vibrating portion, and two covers having a thermal expansion coefficient equal to or greater than 6.times.10.sup.-6 per degrees centigrade and equal to or smaller than 10.times.10.sup.-6 per degrees centigrade and bonded to the supporting portion so as to sandwich the quartz crystal resonator element therebetween.

7608986

Fluorescent fused-ring traizoles that inhibit cell proliferation and uses thereof

2009-10-06T06:18:00.000-07:00

Patent Number: 7598238

Inventor(s): Laskin; Jeffrey D. (Piscataway, NJ), Heindel; Ned (Easton, PA), Heck; Diane (Rumson, NJ), Vetrano; Anna Marie (North Brunswick, NJ), Guillon; Christophe (Bethlehem, PA), DeMatteo; Peter (Allentown, PA)

Date Issued: 10/6/2009

Abstract: Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.

7598238

Fault-tolerant architecture of flip-flops for transient pulses and signal delays

2009-09-22T06:52:00.000-07:00

Patent Number: 7594150

Inventor(s): Chakraborty; Tapan Jyoti (West Windsor, NJ), Jagirdar; Aditya (Highland Park, NJ), Oliveira; Roystein (Highland Park, NJ)

Date Issued: 9/22/2009

Abstract: A method and apparatus for a structure of a flip-flop that is tolerant to the noise pulses occurring due to the presence of crosstalk faults by sampling the input data multiple times before and after the active clock edge. The final stored value at the flip-flop is determined by the resolution of a counter circuit residing in the flip-flop, which is activated at the change of the sampled input data. This counter based resolution mechanism allows for the detection and filtering of the noise pulse induced at the input of the flip-flop due to a crosstalk fault.

7594150

System and method for identifying hierarchical heavy hitters in a multidimensional environment

2009-09-15T06:52:00.000-07:00

Patent Number: 7590657

Inventor(s): Cormode; Graham (Summit, NJ), Korn; Philip Russell (New York, NY), Muthukrishnan; Shanmugavelayutham (Washington, DC), Srivastava; Divesh (Summit, NJ)

Date Issued: 9/15/2009

Abstract: A method including receiving a plurality of elements of a data stream, storing a multi-dimensional data structure in a memory, said multi-dimensional data structure storing the plurality of elements as a hierarchy of nodes, each node having a frequency count corresponding to the number of elements stored therein, comparing the frequency count of each node to a threshold value based on a total number of the elements stored in the nodes and identifying each node for which the frequency count is at least as great as the threshold value as a hierarchical heavy hitter (HHH) node and propagating the frequency count of each non-HHH nodes to its corresponding parent nodes.

7590657

Preparation and uses for polyarylates

2009-09-08T06:52:00.000-07:00

Patent Number: 7585929

Inventor(s): James; Ken (Somerville, MA), Brocchini; Stephen (London, GB), Tangpasuthadol; Varawut (Bangkok, TH), Kohn; Joachim B. (Highland Park, NJ)

Date Issued: 9/8/2009

Abstract: The present invention is directed to polyarylates comprising repeating units having the structure: ##STR00001## as well as their preparation and use as cell growth substrates.

7585929

Piezoelectric vibration angular velocity sensor

2009-08-11T06:52:00.001-07:00

Patent Number: 7571648

Inventor(s): Yong; Yook-Kong (Princeton, NJ), Patel; Mihir S (New Brunswick, NJ), Kanna; Shigeo (Nagano-ken, JP), Tanaka; Masako (Okaya, JP)

Date Issued: 8/11/2009

Abstract: An angular velocity sensor includes a protrusion protruding in a Y'-axis direction and extending in an X-axis direction on a main surface of a rotated Y cut quartz plate, and an excitation electrode and a detection electrode formed on the main surface adjacent to this protrusion. This excitation electrode excites thickness-shear vibration in the X-axis direction on the quartz substrate, exiting vibration on the protrusion. Then, the protrusion is bent and displaced due to Coriolis force acting in a direction orthogonal to the vibration of the protrusion corresponding to a rotation around an Y' axis. This displacement at the protrusion is applied to the quartz substrate as stress. The detection electrode detects change of this stress, thereby angular speed added to the angular velocity sensor is detected.

7571648

Uniform shear application system and methods relating thereto

2009-08-11T06:52:00.000-07:00

Patent Number: 7571871

Inventor(s): Muzzio; Fernando J. (Sparta, NJ), Tsygan; Lev (Brooklyn, NY), Dukler; Semen (Brooklyn, NY)

Date Issued: 8/11/2009

7571871

Methods for measuring capacitance

2009-06-16T06:52:00.000-07:00

Patent Number: 7548067

Inventor(s): Cheung; Kin P. (Hoboken, NJ), Heh; Dawei (Austin, TX), Lee; Byoung Hun (Austin, TX), Choi; Rino (Austin, TX)

Date Issued: 6/16/2009

Abstract: Methods for determining capacitance values of a metal on semiconductor (MOS) structure are provided. A time domain reflectometry circuit may be loaded with a MOS structure. The MOS structure may be biased with various voltages, and reflectometry waveforms from the applied voltage may be collected. The capacitance of the MOS structure may be determined from the reflectometry waveforms.

7548067

Polyanhydrides with therapeutically useful degradation products

2009-05-19T06:52:00.001-07:00

Patent Number: 7534852

Inventor(s): Uhrich; Kathryn E. (Plainfield, NJ)

Date Issued: 5/19/2009

Abstract: An aromatic polyanhydride comprising a repeating unit having the structure ##STR00001## is disclosed, wherein Ar and R are selected so that the aromatic polyanhydride hydrolyzes to form a therapeutic salicylate, another non-steroidal anti-inflammatory, an antifibrotic aminobenzoate, or a vasoconstricting phenylethanolamine. Implantable medical devices, such as scaffolding implants for tissue reconstruction, drug delivery systems prepared from the aromatic polyanhydrides, as well as therapeutic dosage forms and treatment methods are also disclosed.

7534852

Transgenic plants having transformed plastid genomes and progeny thereof

2009-05-19T06:52:00.000-07:00

Patent Number: 7534936

Inventor(s): Maliga; Pal (East Brunswick, NJ), Corneille; Sylvie (Lyons, FR), Lutz; Kerry (Lawrenceville, NJ)

Date Issued: 5/19/2009

Abstract: Plants having transformed plastid genomes comprising a construct comprising attL and attR sites and a gene of interest, where the plants comprise an integrase and, optionally a selectable marker gene, and methods of making the plants.

7534936

Prevention of transgene escape in genetically modified perennials: 7525015

2009-04-28T05:00:00.000-07:00

Inventor(s): Luo Hong, Hu Qian, Vasilchik Kimberly Nelson, Longo John P, Kausch Albert P, Zilinskas Barbara, Lakkaraju Subha

Issued: 4/28/2009

Abstract: Genes can be introduced into plants that confer desirable traits such as, drought and stress tolerance, insect and pest resistance, as well as environmental qualities such as phyto-remediation. However, possibility for transgene escape to wild and non-transformed species raises commercial and ecological concerns. Disclosed herein are methods and compositions for generating sterile plants for the prevention of transgene escape.

The threat of transgene escape to other plants is a real concern, and control of this problem is important if transgenic perennial plants are released. Therefore, methods are needed that decrease or prevent the risk of spreading a transgene from a transgenic perennial into the environment through outcrossing. Disclosed herein are methods for generating sterile plants, such as male sterile plants, which decrease transgene escape. Sterile transgenic plants do not produce significant numbers of viable pollen grains, thus decreasing or preventing the potential risk of transgene escape into the surrounding environment by outcrossing with wild species.

Methods to generate sterile perennial plants, such as male and/or female sterile plants, are disclosed herein by functionally deleting floral structures, such as the tapetum. In one example, a cytotoxic molecule, such as a barnase gene or an anti-sense floral-specific gene, is driven by a floral-specific promoter creating defective floral structures, such as sterile pollen. For example, expression of the cytotoxin, that in one example produces a protein product that decreases the presence and/or production of tapetum, results in male sterility.
USPTO Webpage 7525015

Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix: 7521061

2009-04-21T18:01:00.000-07:00

Inventor(s): Kohn Joachim B, Schachter Deborah M

Issued: 4/21/2009

Abstract: A formulation containing a biologically active compound having a structure with hydrogen bonding sites is blended with a polymer having a structure with complementary hydrogen bonding sites, the polymer forming hydrolytic degradation products that promote the release of the biologically active compound from the polymer.

USPTO Webpage 7521061

Topoisomerase-targeting agents: 7517867

2009-04-14T23:01:00.000-07:00

Inventor(s): LaVoie Edmond J, Ruchelman Alexander L, Liu Leroy F

Issued: 4/14/2009

Abstract: The invention provides compounds of formula I or formula II: ##STR00001## wherein: the bond represented by -- is a single bond or a double bond, and R.sub.1-R.sub.5, X, and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I or II, processes for preparing compounds of formula I or II, intermediates useful for preparing compounds of formula I or II, and therapeutic methods for treating cancer and other topoisomerase related conditions using compounds of formula I or II.

USPTO Webpage 7517867

Solubilized topoisomerase poisons: 7517883

2009-04-14T04:47:00.000-07:00

Inventor(s): LaVoie Edmond J, Ruchelman Alexander L, Liu Leroy F

Issued: 4/14/2009

Abstract: The invention provides compounds of formula I: ##STR00001## whereinA, B, W, Y, Z, and R.sub.1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.

USPTO Webpage 7517883

Translation control elements for high-level protein expression in the plastids of higher plants and methods of use thereof: 7504555

2009-03-17T23:01:00.000-07:00

Inventor(s): Maliga Pal, Kuroda Hiroshi, Khan Muhammad Sarwar

Issued: 3/17/2009

Abstract: DNA constructs containing translational control elements are provided. These 5' regulatory segments facilitate high level expression of transgenes introduced into the plastids of higher plants.

USPTO Webpage 7504555

This invention relates to the fields of transgenic plants and molecular biology. More specifically, the invention provides vectors targeting the plastid genome which contain translation control elements facilitating high levels of protein expression in the plastids of higher plants. Both monocots and dicots are successfully transformed with the DNA constructs provided herein.

Power junction field effect power transistor with highly vertical channel and uniform channel opening: 7479672

2009-01-20T23:01:00.000-08:00

Zhao Jian H

Inventor(s): Zhao Jian H

Issued: 1/20/2009

Abstract: A semiconductor vertical junction field effect power transistor formed by a semiconductor structure having top and bottom surfaces and including a plurality of semiconductor layers with predetermined doping concentrations and thicknesses and comprising at least a bottom layer as drain layer, a middle layer as blocking and channel layer, a top layer as source layer. A plurality of laterally spaced U-shaped trenches with highly vertical side walls defines a plurality of laterally spaced mesas. The mesas are surrounded on the four sides by U-shaped semiconductor regions having conductivity type opposite to that of the mesas forming U-shaped pn junctions and defining a plurality of laterally spaced long and vertical channels with a highly uniform channel opening dimension. A source contact is formed on the top source layer and a drain contact is formed on the bottom drain layer. A gate contact is formed on the bottom of the U-shaped trenches for the purpose of creating and interrupting the vertical channels so as to turn on and turn off the transistor.

USPTO Webpage 7479672

Micelle assemblies: 7470802

2008-12-30T00:01:00.000-08:00

Inventor(s): Uhrich Kathryn E, Tian Lu

Issued: 12/30/2008

Abstract: The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. Also, the invention encompasses compounds of the formula: A-X-Y-Z-R.sub.1 wherein A is a carboxy group or is absent; X is a polyol, Y is --C(.dbd.O)--, --C(.dbd.S)--, or is absent; Z is O, S, or NH; and R.sub.1 is a polyether, wherein one or more hydroxy groups of the polyol are acylated with a fatty acid residue, wherein the compounds form micelle assemblies. The invention encompasses methods of encapsulating molecules using the compounds of the invention.

USPTO Webpage 7470802

Methods and kits for screening nucleic acid duplex stability: 7468250

2008-12-23T00:01:00.000-08:00

Organic Compounds -- Part of the Class 532-570 Series,Breslauer Kenneth J, Gelfand Craig A, Plum Eric G

Inventor(s): Breslauer Kenneth J, Gelfand Craig A, Plum Eric G

Issued: 12/23/2008

Abstract: Simple methods and kits for determining the thermodynamic stability of nucleic acid duplexes and single polynucleotide polymorphisms via competitive equilibria are provided.

USPTO Webpage 7468250

Plastid promoters for transgene expression in the plastids of higher plants: 7452986

2008-11-18T00:01:00.000-08:00

Chemistry: Natural Resins or Derivatives; Peptides or Proteins; Lignins or Reaction Products Thereof,Maliga Pal, Silhavy Daniel, Sriraman Priya

Inventor(s): Maliga Pal, Silhavy Daniel, Sriraman Priya

Issued: 11/18/2008

Abstract: The present invention provides promoter elements useful for stably transforming the plastids of higher plants. The constructs described herein contain unique promoters that are transcribed by both nuclear encoded plastid RNA polymerases, plastid encoded plastid RNA polymerases or both. Use of the novel constructs of the invention facilitates transformation of a wider range of plant species and enables ubiquitous expression of a transforming DNA in plastids of multicellular plants.

USPTO Webpage 7452986

Mutational derivatives of microcin J25: 7442762

2008-10-28T23:44:00.000-07:00

Inventor(s): Severinov Konstantin, Ebright Richard, Pavlova Olga, Sineva Elena

Issued: 10/28/2008

Abstract: Analogs of bacteriocidal peptide microcin J25 (MccJ25) are provided that have an amino acid sequence that differs from that of MccJ25 by having at least one amino acid substitution; and that inhibit bacterial cell growth with a potency at least equal to that of MccJ25.

Applicants have discovered analogs of MccJ25 that are able to bind to bacterial RNAP, to inhibit bacterial RNAP, and to inhibit bacterial growth with a potency at least equal to that of mature MccJ25 (FIG. 1).

The present invention provides an analog of bacteriocidal peptide microcin J25 (MccJ25) that (1) has an amino acid sequence that differs from that of MccJ25 by having at least one amino acid substitution; and (2) that inhibits bacterial cell growth with a potency at least equal to that of MccJ25.

The present invention also provides a method of identifying at least one MccJ25 analog that inhibits growth of MccJ25-sensitive cells. This method includes growing MccJ25-sensitive cells in the presence of cells harboring a plasmid containing an MccJ25 analog, the analog having an amino acid sequence that differs from that of MccJ25 by having at least one amino acid substitution; and observing the presence or absence of cell growth inhibition, wherein the presence of cell growth inhibition indicates the presence of cells producing the MccJ25 analog that inhibits growth of MccJ25-sensitive cells.

The invention further provides a method of identifying at least one MccJ25 analog that inhibits cell growth of MccJ25-resistant cells. This method includes growing MccJ25-resistant cells in the presence of cells harboring a plasmid containing an MccJ25 analog, the analog having an amino acid sequence that differs from that of MccJ25 by having at least one amino acid substitution. The method also includes observing the presence or absence of cell growth inhibition, wherein the presence of cell growth inhibition indicates the presence of cells producing the MccJ25 analog that inhibits growth of MccJ25-resistant cells.

It is anticipated that compounds and methods of this invention would have applications not only in antibacterial therapy, but also in: (a) identification of bacterial RNAP (diagnostics, environmental-monitoring, and sensors applications), (b) labeling of bacterial RNAP (diagnostics, environmental-monitoring, imaging, and sensors applications), (c) immobilization of bacterial RNAP (diagnostics, environmental-monitoring, and sensors applications), (d) purification of bacterial RNA polymerase (biotechnology applications), (e) regulation of bacterial gene expression (biotechnology applications), and (f) antisepsis (antiseptics, disinfectants, and advanced-materials applications).

USPTO Webpage 7442762

Peach tree named `NJ350`: PP19,382

2008-10-28T03:46:00.000-07:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 10/28/2008

Abstract: A new and distinct peach variety of Prunus persica named `NJ350` is provided. This variety is distinguished from other peach varieties by its unique combination of nonshowy flowers, fruit that ripen early in the season, attractive fruit with an orange-red ground color, clingstone fruit with a juicy, melting texture and moderately acidic flavor, and good production of firm fruit with a low incidence of split pits for the season.

USPTO Webpage PP19,382

Three-phase partitioning method for purifying a protein: 7439337

2008-10-21T03:47:00.000-07:00

Inventor(s): Ward William W

Issued: 10/21/2008

Abstract: The present invention is a kit and method for purifying a protein of interest.

There is a growing need in the biotechnology, biopharmaceutical, and research fields for a fast, efficient, versatile, and inexpensive low volume, one-step, micro-scale method, in kit form, to prepare small quantities of proteins for early-stage exploratory research. To move forward with early-stage exploratory research, it is essential to be able to quantitate the levels of the proteins of interest and to remove substances that might interfere with the properties and functions of these proteins. Protein quantitation is often accomplished via in vitro quantitative assays such as those employing optical detection methods. Such assay methods include, but are not limited to, colorimetry, fluorimetry, spectrophotometry, microtitre plate scanning, and optical microfluidics. Each of these optical assay methods suffers greatly in accuracy, producing falsely high and, on occasion, falsely low signals, if the sample in question contains unwanted, optically absorptive contaminants or if the sample is cloudy or turbid. Specific interference may occur, on a case-by-case basis, from substances that chemically react with assay reagents or that inhibit development of the assay in some fashion, as in the case of enzyme inhibitors. Thus, for accurate quantification of the protein of interest, removal of such contaminants is essential.

USPTO Webpage 7439337

Peach tree named `NJF18`: PP19,273

2008-09-30T16:08:00.000-07:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 9/30/2008

Abstract: A new and distinct peach variety of Prunus persica named `NJF18` is provided. This variety is distinguished from other peach varieties by its unique combination of showy flowers that are medium in width, flat fruit that ripen in early midseason with mottled red over color on an attractive orange ground color, semi-clingstone fruit with a juicy, melting texture and sweet, mild flavor, firm fruit that retain their firmness well and trees with regular, heavy production of large fruit.

USPTO Webpage PP19,273

Synthesis of polyanhydrides: 7411031

2008-08-12T17:01:00.000-07:00

Inventor(s): Uhrich Kathryn E, Schmeltzer Robert C, Anastasiou Theodore James

Issued: 8/12/2008

Abstract: The present invention provides a method for forming compounds of Formula HO--C(.dbd.O)R.sup.1--X--R.sup.2--X--R.sup.1--C(.dbd.O)--O--H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R.sup.1 is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R.sup.2 is a linking group.

USPTO Webpage 7411031

Nanostructured re-doped SiO.sub.2-base fluorescent materials and methods for production of same: 7407604

2008-08-05T17:01:00.000-07:00

Inventor(s): Kear Bernard H, Haines Christopher D, Sigel George H, Klein Lisa C, Ranganathan Varadh

Issued: 8/5/2008

Abstract: A new class of nanostructured RE-doped SiO.sub.2-base materials that display superior fluorescence properties is provided. In particular, high gain combined with a broad and flat spectral band width is observed in material composed of a high fraction of a nano-dispersed metastable silicate phase in a glassy SiO.sub.2 matrix, produced by partial devitrification (crystallization) of several glassy Al.sub.2O.sub.3/Er.sub.2O.sub.3- and Y.sub.2O.sub.3/Er.sub.2O.sub.3-doped SiO.sub.2 compositions. Also, a highly deconvoluted spectral emission, with several prominent peaks, is observed in completely devitrified material, consisting of a uniform nano-dispersion of an equilibrium silicate phase in a crystobalite SiO.sub.2 matrix. Such enhanced fluorescence properties were observed in heat treated nanopowders prepared by vapor-phase, solgel, rapid solidification, and spray-pyrolysis methods.

USPTO Webpage 7407604

Schottky diode with silver layer contacting the ZnO and Mg.sub.xZn.sub.1-xO films: 7400030

2008-07-15T17:01:00.000-07:00

Inventor(s): Lu Yicheng, Sheng Haifeng, Muthukumar Sriram, Emanetoglu Nuri William, Zhong Jian, Liang Shaohua

Issued: 7/15/2008

Abstract: In the present invention, there is provided semiconductor devices such as a Schottky UV photodetector fabricated on n-type ZnO and Mg.sub.xZn.sub.1-xO epitaxial films. The ZnO and Mg.sub.xZn.sub.1-xO films are grown on R-plane sapphire substrates and the Schottky diodes are fabricated on the ZnO and Mg.sub.xZn.sub.1-xO films using silver and aluminum as Schottky and ohmic contact metals, respectively. The Schottky diodes have circular patterns, where the inner circle is the Schottky contact, and the outside ring is the ohmic contact. Ag Schottky contact patterns are fabricated using standard liftoff techniques, while the Al ohmic contact patterns are formed using wet chemical etching. These detectors show low frequency photoresponsivity, high speed photoresponse, lower leakage current and low noise performance as compared to their photoconductive counterparts. This invention is also applicable to optical modulators, Metal Semiconductor Field Effect Transistors (MESFETs) and more.

USPTO Webpage 7400030

Antibiotic polymers: 7396527

2008-07-08T17:01:00.000-07:00

Inventor(s): Uhrich Kathryn E

Issued: 7/8/2008

Abstract: Polymers (i.e. polyesters, polyamides, polythioesters, polyanhydrides, or a mixture thereof) which degrade hydrolytically to provide a combination of a beta-lactam antibiotic (e.g., amoxicillin) and a beta-lactamase inhibitor (e.g., clavulanic acid) (or a pharmaceutically acceptable salt thereof) are provided. Methods of producing these polymers, intermediates useful for preparing these polymers, and methods of using these polymers to deliver a combination of a beta-lactam antibiotic and a beta-lactamase inhibitor (or a pharmaceutically acceptable salt thereof) to a host are also provided.

USPTO Webpage 7396527

Animal model, cells, and treatment for malignant melanoma: 7385103

2008-06-10T18:01:00.000-07:00

Inventor(s): Chen Suzie

Issued: 6/10/2008

Abstract: The present invention provides transgenic non-human animal models and cell lines which express a metabotropic glutamate receptor 1 in a melanocyte-specific manner and, as a result, exhibit a predisposition to the development of melanoma. The invention further teaches methods of using the transgenic animals and cell lines to identify therapeutic agents. Diagnostic methods for detecting a melanoma are also provided.

USPTO Webpage 7385103

Reagents and procedures for multi-label high-specificity labeling: 7381572

2008-06-03T18:01:00.000-07:00

Inventor(s): Ebright Richard H, Ebright Yon W

Issued: 6/3/2008

Abstract: A detectable complex and methods for use thereof are provided herein. The detectable complex includes: at least one target material; a first peptide tag bound to the at least one target material; and a second peptide tag bound to the at least one target material. The complex further includes a first conjugate having a detectable group and two pendant phenylarsine moieties comprising a first tag binding group; wherein the first conjugate preferentially associates with the first peptide tag; and a second conjugate having a detectable group and two pendant phenylarsine moieties comprising a second tag binding group; wherein the second conjugate preferentially associates with the second peptide tag. The mean distance and/or mean angle between the pendant phenylarsine moieties in the first conjugate is different from the mean distance and/or mean angle between the pendant phenylarsine moieties in the second conjugate. Further provided herein are useful peptide tag combinations, target materials or sets of target materials including these peptide tag combinations, and nucleic acids or nucleic acid sets encoding these compositions.

USPTO Webpage 7381572

Antioxidant and anti-inflammatory activity of compounds and preparations from African nutmeg seeds: 7371413

2008-05-13T19:01:00.001-07:00

Inventor(s): Simon James E, Wang Mingfu, Gbewonyo Kodzo, Rafi Mohamed M, Acquaye Daniel Fahene, Asianowa Yaw

Issued: 5/13/2008

Abstract: The present invention provides methods for reducing the production of nitric oxide, inducible nitric oxide synthase protein and mRNA, and cyclooxygenase-2 protein and mRNA in cells both in vivo and in vitro via the administration of extracts and compounds derived from the seeds of Pycnanthus angolensis Warb. (P. Kombo), commonly known as African nutmeg. These extracts and compounds, namely, kombo butter, kombo butter acid extract, sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, are also useful in the treatment and prevention of a battery of adverse health conditions in human, animal, and avian subjects that are advanced by the production of nitric oxide or its metabolites and/or by the activity of cyclooxygenase-2. Methods for the isolation of kombo butter acid extracts are also provided.

USPTO Webpage 7371413

Metal fluorides as electrode materials: 7371338

2008-05-13T19:01:00.000-07:00

Inventor(s): Amatucci Glenn G

Issued: 5/13/2008

Abstract: Safe and economical electrochemically active nanocomposites based on metal fluoride compounds useful in rechargeable battery cell electrodes. When incorporated as the active electrode material in lithium battery cell systems, the nanocomposites enable high, stable specific capacities.

USPTO Webpage 7371338

MAGE-A3 peptides presented by HLA class II molecules: 7371845

2008-05-13T18:01:00.000-07:00

Inventor(s): Zhang Yi, Chaux Pascal, Boon-Falleur Thierry, Bruggen Pierre Van Der

Issued: 5/13/2008

Abstract: The invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4.sup.+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-A3 gene.

USPTO Webpage 7371845

Hydrazide compounds with angiogenic activity: 7368169

2008-05-06T19:01:00.000-07:00

Inventor(s): Kohn Joachim B, Labazzo Kristen S, Bolikal Durgadas

Issued: 5/6/2008

USPTO Webpage 7368169

Field-effect transistors with weakly coupled layered inorganic semiconductors: 7361929

2008-04-22T19:01:00.000-07:00

Inventor(s): Bucher Ernst, Gershenson Michael E, Kloc Christian, Podzorov Vitaly

Issued: 4/22/2008

USPTO Webpage 7361929

Fluorescent Protein From Montastraea Cavernosa: 7358336

2008-04-15T20:01:00.000-07:00

Inventor(s): Falkowski Paul, Sun Yi, Gorbunov Maxim, Wyman Kevin, Chen Yi-Bu

Issued: 4/15/2008

Abstract: mcFP encoding nucleic acids, polypeptides and antibodies immunologically specific therefore are disclosed. Methods of use thereof are also provided.

USPTO Webpage 7358336

Bioactive compounds and methods of uses thereof: 7351739

2008-04-01T20:01:00.000-07:00

Inventor(s): Ho Chi-Tang, Bai Naisheng, Dong Zigang, Bode Ann M, Dushenkov Slavik

Issued: 4/1/2008

Abstract: In one aspect, the present invention provides compounds having formula I or IV as shown below: ##STR00001## as further defined herein. In additional aspects, the present invention provides compositions and kits comprising the compounds of the invention and methods for their use, for example, for the prevention or treatment of a cancer.

USPTO Webpage 7351739

Methods for identifying agonists of cypin: 7338769

2008-03-04T20:01:00.000-08:00

Inventor(s): Firestein-Miller Bonnie

Issued: 3/4/2008

Abstract: Disclosed are novel materials and screening methods for diagnosing and monitoring cognitive disorders, as well as for identifying compounds for treating such disorders.

USPTO Webpage 7338769

Apparatuses and methods for determining protease activity: 7329506

2008-02-12T04:47:00.000-08:00

Inventor(s): Ward William W, Swiatek Gavin C

Issued: 2/12/2008

USPTO Webpage 7329506

Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release: 7326425

2008-02-05T04:47:00.000-08:00

Inventor(s): Kohn Joachim B, Schachter Deborah M

Issued: 2/5/2008

Abstract: A formulation containing a biologically active compound having a structure with hydrogen bonding sites blended with a first polymer having a structure with complementary hydrogen bonding sites and a second polymer that degrades to form degradation products that promote the release of the active compound from the first polymer.

USPTO Webpage 7326425

Cytotoxic agents: 7319105

2008-01-15T04:47:00.000-08:00

LaVoie Edmond J, Ruchelman Alexander L, Singh Sudhir K, Ray Abhijit, Liu Leroy F

Inventor(s): LaVoie Edmond J, Ruchelman Alexander L, Singh Sudhir K, Ray Abhijit, Liu Leroy F

Issued: 1/15/2008

Abstract: The invention provides compounds of the invention pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer and other topoisomerase mediated conditions.

USPTO Webpage 7319105

Asparagus plant named `NJ44P`: PP18,409

2008-01-08T04:47:00.000-08:00

Inventor(s): Garrison Stephen A, Chin Chee-kok, Kinelski John J

Issued: 1/8/2008

Abstract: A female asparagus plant (Asparagus officinalis) denoted `NJ44P` was developed through extensive culture and selection from a field of the variety Mary Washington. Plant `NJ44P` has many desirable traits including vigorous plant growth, high yield, good resistance to rust (Puccinia asparagi) and good field tolerance to asparagus root rot (Fusarium oxysporum) and asparagus crown rot (Fusarium mondiforme). These desirable traits have been shown to be transmissible to its progenies. The invention relates to plants and plant parts of `NJ44P` plant. The invention further relates to hybrid asparagus seeds and plants produced by crossing the asparagus `NJ44P` plant with another asparagus plant.

USPTO Webpage PP18,409

Homozygous male asparagus plant named `NJ22-34`: PP18,387

2008-01-01T22:01:00.000-08:00

Plants,Garrison Stephen A, Chin Chee-kok, Kinelski John J

Inventor(s): Garrison Stephen A, Chin Chee-kok, Kinelski John J

Issued: 1/1/2008

Abstract: A new and distinct asparagus (Asparagus officinalis Linn.) plant denoted `NJ22-34` which is homozygous for male sex gene was developed through extensive breeding and selection. Asparagus hybrid `NJ22-34` has many desirable traits including homogenous in male genes, good resistance to rust (Puccinia asparagi) and good field tolerance to asparagus root rot (Fusarium oxysporum) and asparagus crown rot (Fusarium moniliforme). Because `NJ22-34` is a homozygous-male plant all its F1 progenies will be male plants. This invention relates to the plant and plant parts of `NJ22-34`. The invention further relates to hybrid asparagus seeds and plants produced by crossing asparagus plant `NJ22-34` with another asparagus plant.

USPTO Webpage PP18,387

Method, and article of the method, for fabricating a flexible, hollow waveguide: 7315675

2008-01-01T05:06:00.000-08:00

Harrington James A, Gopal Veena

Inventor(s): Harrington James A, Gopal Veena

Issued: 1/1/2008

Abstract: A flexible, hollow, waveguide is featured, that functions in the visible region. The waveguide comprises a hollow, flexible, silica-glass tube having a smooth bore, that is coated with a reflective substance on the inner bore surface. A composite of two sulfide materials are then layered over the reflective substance. The sulfide materials form a high contrasting refractive index of approximately 2:1, thus creating a photonic, bandgap tube.

USPTO Webpage 7315675

Topical anti-cancer compositions and methods of use thereof: 7309688

2007-12-18T22:01:00.000-08:00

Organic Compounds -- Part of the Class 532-570 Series,Seiberg Miri, Shapiro Stanley S, Paine Christine, Conney Allan H, Huang Mou-Tuan

Inventor(s): Seiberg Miri, Shapiro Stanley S, Paine Christine, Conney Allan H, Huang Mou-Tuan

Issued: 12/18/2007

Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.

USPTO Webpage 7309688

Cranberry variety named `NJS98-23`: PP18,252

2007-11-27T22:01:00.000-08:00

Plants,Vorsa Nicholi

Inventor(s): Vorsa Nicholi

Issued: 11/27/2007

Abstract: A new cranberry variety distinguished by significantly higher yields, higher anthocyanin (red pigment) content, and higher stolon vigor as compared to the currently cultivated commercial varieties.

USPTO Webpage PP18,252

Peach tree named `NJ351`: PP18,224

2007-11-20T23:01:00.000-08:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 11/20/2007

Abstract: A new and distinct peach variety of Prunus persica named `NJ351` is provided. This variety is distinguished from other peach varieties by its unique combination of nonshowy flowers, fruit that ripen in late-midseason, attractively blushed fruit with a bright golden-yellow ground color, freestone fruit with a juicy, nearly nonmelting texture and sweet, low acid flavor, firm fruit that retain their firmness well and trees with regular, heavy production of fruit.

USPTO Webpage PP18,224

Benzotropolone derivatives and modulation of inflammatory response: 7288680

2007-10-30T23:01:00.001-07:00

Inventor(s): Ho Chi-Tang, Ghai Geetha, Sang Shengmin, Jhoo Jin-Woo, Huang Mou-Tuan, Rosen Robert T, Dushenkov Slavik

Issued: 10/30/2007

Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: ##STR00001## including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.

USPTO Webpage 7288680

Nectarine tree named `NJN100`: PP18,147

2007-10-30T23:01:00.000-07:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 10/30/2007

Abstract: A new and distinct nectarine variety of Prunus persica named `NJN100` is provided. This variety is distinguished from other nectarine varieties by its unique combination of showy flowers, fruit that ripen in early-season, glossy fruit with an attractive red over color and greyed-white ground color, clingstone fruit with a juicy, melting texture and sweet, moderately acidic flavor, and excellent production of firm fruit that maintain their eating quality following cold storage.

USPTO Webpage PP18,147

Peach tree named `NJ353`: PP18,134

2007-10-23T23:01:00.001-07:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 10/23/2007

Abstract: A new and distinct peach variety of Prunus persica named `NJ353` is provided. This variety is distinguished from other peach varieties by its unique combination of showy flowers, fruit that ripen in late-season, attractive fruit with a yellow-orange ground color, freestone fruit with a juicy, melting texture and moderately acidic flavor, and good production of firm fruit that maintain their eating quality following cold storage.

USPTO Webpage PP18,134

Plastid directed DNA constructs comprising chimeric plastid targeting regions, vectors containing same and methods of use thereof: 7285700

2007-10-23T23:01:00.000-07:00

Inventor(s): Maliga Pal, Skarjinskaia Marina, Maliga Zora Svab

Issued: 10/23/2007

Abstract: This invention relates to methods and compositions for obtaining Arabidopsis and Brassica plants. Specifically, the method provides culturing protocols and compositions that facilitate the regeneration of transformed plants following delivery of beneficial DNA molecules.

USPTO Webpage 7285700

Ultra-high specificity fluorescent labeling: 7282373

2007-10-16T23:01:00.000-07:00

Ebright Richard H, Ebright Yon W

Inventor(s): Ebright Richard H, Ebright Yon W

Issued: 10/16/2007

Abstract: A self-assembled relay probe for detecting a target material is provided including: a first peptide tag bound to the target material; and a first fluorescent conjugate including a first fluorochrome and a first tag binding group; wherein the first fluorescent conjugate selectively associates with the first tag. The probe further includes a second peptide tag bound to the target material; and a second fluorescent conjugate including a second fluorochrome having a longer wavelength and distinct excitation and emission maxima from the first fluorochrome and a second tag binding group. Upon exposure to the target material, the first and second fluorescent conjugates independently associate with the first and second peptide tags, respectively, so as to be a distance apart represented by about 0.1 times R.sub.0 to about 2 times R.sub.0, such that upon excitation of the first fluorescent conjugate, fluorescence resonance energy transfer results in excitation of the second fluorescent conjugate, yielding detectable emission from the second fluorescent conjugate.

USPTO Webpage 7282373

Peach tree named `NJ352`: PP18,091

2007-09-25T23:01:00.000-07:00

Inventor(s): Goffreda Joseph C, Voordeckers Anna M

Issued: 9/25/2007

Abstract: A new and distinct peach variety of Prunus persica named `NJ352` is provided. This variety is distinguished from other peach varieties by its unique combination of nonshowy flowers, fruit that ripen in latter part of mid-season, attractive fruit with a yellow-orange ground color, freestone fruit with a juicy, melting texture and moderately acidic flavor, and good production of firm fruit.

USPTO Webpage PP18,091

Polyarylates for drug delivery and tissue engineering: 7271234

2007-09-18T23:01:00.001-07:00

Inventor(s): Kohn Joachim B, Pulapura Satish, Schwartz Arthur, Bahulekar Raman

Issued: 9/18/2007

Abstract: Biocompatible polyarylates of tyrosine-derived diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed.

USPTO Webpage 7271234